Endocrine Abstracts

Introduction: The neuroendocrine tumor of the ampulla of Vater represent a very rare disease, corresponding up to 2% of the periampullary malignancies and less than 1% of gastrointestinal NET. Less than 130 patients have been reported until 2013. The biological and clinical behavior is very unpredictable especially if it’s associated with another tumor, like adenocarcinoma. We present a case of a fifty-one-years-old woman who complained of weight loss, jaundice, abdominal...

Neuroendocrine tumors (NETs) includes a broad family of tumors, the most frequent ones are in the gastrointestinal tract, lung, thymus, and pancreas. Gas-trointestinal and Pulmonary NETs may present with symptoms attributable to hormonal hypersecretion, which include intermit-tent flushing and diarrhea, or symptoms related to Cushing Syndrome. The variability of clinical manifestation may lead to late referral or misdiagnosis. In this retrospective study we analyzed 27 patient...

Introduction: Persistent or intermittent postoperative discordance between growth hormone (GH) after OGTT and insulin-like growth factor-1 adjusted for age and gender (IGF-1) is up to 39% according to different studies. The aim of this study was to evaluate the impact of this discrepancy (normal GH and elevated IGF1 or vice versa) over the risk of biochemical and tumour recurrence after initial successful surgery for acromegaly.Methods: In this retrospec...

Introduction: Medullary thyroid cancer (MTC) is a neuroendocrine tumor of the parafollicular or C cells of the thyroid gland. While thyroid cancer is increasingly common worldwide, MTC still has a low incidence. We present a case of a seventy-one-years-old woman who presented in our unit after an axillary adenopathy biopsy which tested sparsely positive for KeratinPan, CK7, CEA, TTF1, Chromogranin, Snaptophysin and calcitonin, focal positive for EMA, PAX8, Ki67 30%. Also multi...

IntroductionOver time, different substances and protocols have been used and tested for stimulating calcitonin (CT). Some of them proved to be useful in diagnosing medullary thyroid carcinoma (MTC). However, these are associated with side-effects, with various duration, intensity and severity.ObjectiveTo report the side-effects observed during CT stimulation test with calcium (Ca) gluconate.<p class="abst...

Introduction: Thresholds of basal (bCT) or stimulated serum calcitonin (sCT) levels for the diagnosis of medullary thyroid carcinoma (MTC) aren’t specified in current revised MTC guidelines.Objective: We aim to setfemale (F) specific thresholds for bCT and sCT for MTC diagnosis.Methods: CT samples were measured during calcium-stimulation test (25 mg/kg BW adapted to ideal body mass index) before and at 2, 5 and 10 minutes afte...